Nonetheless PCR assays involve prior understanding of likely contaminants and only detect viral nucleic acids. HTS supplies a better breadth of detection than PCR and is also observing common fascination from the vaccine and recombinant protein industry59. Having said that, latest HTS sample planning ways and bioinformatic pipelines will not be as

Despite the fact that Uncooked elements have been identified for being the most possible source of your contamination in eleven events, testing Those people Uncooked materials did not automatically detect the contaminating virus. In only three activities was the viral contaminant specifically detected from the suspect raw materials (Fig.The in vitr